The papers in this volume were presented at the 2nd International Conference on Wireless Information Networks & Business Information System (WINBIS 2010), held in Kathmandu, Nepal, 28th Feb - 1st March, 2010.

This year, the conference research track received a total of 38 submissions, out of which 15 were accepted. This amounts to an acceptance rate of about 40 %, confirming the reputation of the WINBIS'10 conference as being quite selective! The program committee consisted of 30 members, leading to 10--15 articles to be reviewed by each PC member. While such load is not inconsistent with previous editions of WINBIS'09 . The chair is particularly grateful to the PC members which have taken the time to carefully consider papers and debate each other's arguments. Given the high number of interesting submissions, the PC has worked with the chair to select the best submissions, and did not consider issues such as the overall balance of various database research areas in the conference program.